Childhood non-Hodgkin’s lymphoma is a disease in which malignant cells form in the lymph system. Because lymph tissue is found throughout the entire body, childhood non-Hodgkin’s lymphoma can begin almost anywhere. Cancer can spread to the liver, as well as many other organs and tissues.
In children, non-Hodgkin's lymphoma is classified as one of the following:
- Large cell or diffuse histiocytic non-Hodgkin’s lymphoma: Children with this type of non-Hodgkin’s lymphoma usually have lymphatic system involvement, as well as a non-lymph structure involvement.
- Small non-cleaved cell lymphoma (Burkitt's or non-Burkitt's): This type of lymphoma is usually characterized by a large abdominal tumor, and possibly bone marrow and central nervous system involvement.
- Lymphoblastic lymphoma: Lymphoblastic non-Hodgkin lymphoma usually presents with a mass in the chest, swollen lymph node(s), with or without bone marrow and central nervous system involvement.