Saint Francis Health System

Surgery Research Portfolio

The surgery research portfolio includes studies focused on vascular and endovascular interventions for patients with deep vein thrombosis, acute lower extremity arterial occlusions, and carotid artery stenosis. These trials evaluate device-based approaches such as thrombectomy systems and carotid artery stenting technologies, with the goal of improving vessel patency, treatment safety, and clinical outcomes for patients with complex vascular disease.

The surgery research portfolio includes studies focused on vascular and endovascular interventions for patients with deep vein thrombosis, acute lower extremity arterial occlusions, and carotid artery stenosis. These trials evaluate device-based approaches such as thrombectomy systems and carotid artery stenting technologies, with the goal of improving vessel patency, treatment safety, and clinical outcomes for patients with complex vascular disease.

DEFIANCE- NCT05701917 Prospective, Multicenter, randomized controlled trial of an interventional strategy using the ClotTriever System to achieve and maintain vessel patency (ClotTriever Intervention Arm) versus conservative medical management using anticoagulation therapy alone (Conservative Medical Management Arm) in the treatment of subjects with symptomatic unilateral iliofemoral DVT. 1:1, ClotTriever Intervention Arm or Conservative Medical Management Arm.

Study Details | NCT05701917 | DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombosis | ClinicalTrials.gov

ArtixASCEND- NCT07135895 Prospective, post-market, multicenter, single-arm study to evaluate the safety and effectiveness of the Artix Thrombectomy System in patients with acute lower extremity arterial occlusions. The Artix All-in-one Solution for Complete thrombEctomy With eNDovascular Approach

Study Details | NCT07135895 | The ArtixASCEND Study | ClinicalTrials.gov

PERFORMANCE III- NCT05845710 A prospective, multicenter, single-arm, open-label study evaluating the safety and effectiveness of the Neuroguard IEP® Direct System for the treatment of carotid artery stenosis in subjects at elevated risk for carotid endarterectomy (CEA). 

Study Details | NCT05845710 | Direct Access Carotid Artery Stenting Using the Neuroguard IEP System (PERFORMANCE III) | ClinicalTrials.gov